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EDUCATION AND RESEARCH EXPERIENCE
| 1989-1993 |
B.S., Wuhan University |
| 1993-1996 |
M.S. Wuhan University |
| 1996-2000 |
Ph.D. Fudan University |
| 2000-2002 |
Research Fellow, University of Sussex, England |
| 2002-2003 |
Research Associate, University of Delaware |
| 2004-present |
Professor, University of Science and Technology of China |
RESEARCH INTERESTS
| 1) |
Controlled Synthesis of Polymers with Complex Architectures |
| 2) |
Chemosensors and Biosensors for Clinical Diagnostics |
| 3) |
Supramolecular Self-Assembly and Functional Materials |
| 4) |
Kinetics of Chain Folding, Aggregation, and Assembly |
| 5) |
Biomaterials, Nanomedicine, Bioimaging |
CURRENT RESEARCH PROJECTS
REPRESENTATIVE PUBLICATIONS
| 1) |
X. R. Wang, J. M. Hu, G. H. Liu, J. Tian, H. J. Wang, M. Gong, S. Y. Liu* "Reversibly Switching Bilayer Permeability and Release Modules of Photochromic Polymersomes Stabilized by Cooperative Noncovalent Interactions", J. Am. Chem. Soc. 2015, 137, 15262-15275. |
| 2) |
G. H. Liu, G. F. Zhang, J. M. Hu, X. R. Wang, M. Q. Zhu, S. Y. Liu* "Hyperbranched Self-Immolative Polymers (hSIPs) for Programmed Payload Delivery and Ultrasensitive Detection", J. Am. Chem. Soc. 2015, 137, 11645-11655. |
| 3) |
X. L. Hu, G. H. Liu, Y. Li, X. R. Wang, S. Y. Liu* “Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals”J. Am. Chem. Soc.2015, 137,362-368 (JACS Spotlights). |
| 4) |
Y. M. Li, G. H. Liu, X. R. Wang, J. M. Hu, S. Y. Liu* "Enzyme-Responsive Polymeric Vesicles for Bacterial Strain-Selective Delivery of Antimicrobial Agents", Angew. Chem. Int. Ed. DOI: 10.1002/anie.201509401 (2015) |
| 5） |
Y. M. Li, H. S. Yu, Y. F. Qian, J. M. Hu, S. Y. Liu*“Amphiphilic Star Copolymer-Based Bimodal Fluorogenic/Magnetic Resonance Probes for Concomitant Bacteria Detection and Inhibition” Adv. Mater.2014, 26, 6734-6741. |
| 6) |
X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu*“Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission” J. Am. Chem. Soc.2014, 136, 9890-9893. |
| 7) |
G. H. Liu, X. R. Wang, J. M. Hu, G. Y. Zhang, S. Y. Liu* “Self-Immolative Polymersomes for High-Efficiency Triggered Release and Programmed Enzymatic Reactions” J. Am. Chem. Soc.2014, 136, 7492-7497. |
| 8) |
X. R. Wang, G. H. Liu, J. M. Hu, G. Y. Zhang, S. Y. Liu* “Concurrent Block Copolymer Polymersome Stabilization and Bilayer Permeabilization via Stimuli-Regulated ‘Traceless’ Crosslinking” Angew. Chem. Int. Ed. 2014, 53, 3138-3142. |
| 9) |
X. L. Hu, J. M. Hu*, J. Tian, Z. S. Ge, G. Y. Zhang, K. F. Luo, S. Y. Liu*"Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking and Drug Delivery", J. Am. Chem. Soc.2013, 135, 17617-17629 (SciBX). |
| 10) |
J. M. Hu, T. Wu, G. Y. Zhang, S. Y. Liu*"Efficient Synthesis of Single Gold Nanoparticle Hybrid Amphiphilic Triblock Copolymers and Their Controlled Self-Assembly",J. Am. Chem. Soc. 2012,134, 7624-7627. |
| 11) |
G. C. Yu, C. Y. Han, Z. B. Zhang, J. Z. Chen, X. Z. Yan, B. Zhang, S. Y. Liu*, F. H. Huang* "Pillar[6]arene-Based Photo-Responsive Host-Guest Complexation", J. Am. Chem. Soc.2012,134, 8711-8717. |
| 12) |
C. H. Li, T. Wu, C. Y. Hong, G. Q. Zhang, S. Y. Liu*"A General Strategy to Construct Fluorogenic Probes from Charge-Generation Polymers (CGPs) and AIE-Active Fluorogens via Triggered Complexation",Angew. Chem. Int. Ed., 2012,51, 455-459. |
| 13) |
C. H. Li, Y. X. Zhang, J. M. Hu, J. J. Cheng*, S. Y. Liu*, "Reversible Three-State Switching of Multicolor Fluorescence Emission via Multiple Stimuli-Modulated FRET Processes within Thermoresponsive Polymeric Micelles",Angew. Chem. Int. Ed., 2010,49, 5120-5124. |
| 14） |
Z. S. Ge, Y. M. Zhou, J. Xu, H. W. Liu, D. Y. Chen*, S. Y. Liu*“High-Efficiency Preparation of Macrocyclic Diblock Copolymers via Selective Click Reaction in Micellar Media” J. Am. Chem. Soc.2009, 131, 1628-1629. |
| 15） |
Z. S. Ge, J. M. Hu, F. H. Huang*, S. Y. Liu*“Responsive Supramolecular Gels Constructed via Crown Ether-Based Molecular Recognition” Angew. Chem. Int. Ed.2009, 48, 1798-1802. |
| 16） |
J. Xu, Z. Y. Zhu, S. Z. Luo, C. Wu, S. Y. Liu* “First observation of two-stage collapsing kinetics of a single synthetic polymer chain” Phys. Rev. Lett. 2006, 96, 027802. |
| 17） |
J. M. Hu, S. Y. Liu* “Engineering Responsive Polymer Building Blocks with Host-Guest Molecular Recognition for Functional Applications” Acc. Chem. Res.2014, 47, 2084-2095 |
| 18） |
J. M. Hu, G. Y. Zhang, Z. S. Ge, S. Y. Liu* “Stimuli-Responsive Tertiary Amine Methacrylate-Based Block Copolymers: Synthesis, Supramolecular Self-Assembly and Functional Applications” Prog. Polym. Sci. 2014, 39, 1096-1143. |
| 19） |
Z. S. Ge*, S. Y. Liu* “Functional Block Copolymer Assemblies Responsive to Tumor and Intracellular Microenvironments for Site-Specific Drug Delivery and Enhanced Imaging Performance” Chem. Soc. Rev. 2013, 42, 7289-7325. |
| 20） |
J. M. Hu, G. Q. Zhang, S. Y. Liu* “Enzyme-Responsive Polymeric Assemblies, Nanoparticles and Hydrogels” Chem. Soc. Rev. 2012, 41, 5933-5949. |
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